Steroids and derivatives
Cayman Chemical DecnoIc AcId-d3 10mg
An internal standard for the quantification of decanoic acid by GC- or LC-MS
Medchemexpress LLC Cinacalcet-d3 hydrochloride | 364782-34-3 | 97.6% | C22H20D3ClF3N | 500 UG
Cinacalcet-d3 (hydrochloride) is the deuterium labeled Cinacalcet (hydrochloride). It is an orally active, allosteric agonist of the Ca receptor (CaR), used for cardiovascular disease treatment. Deuteration has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Isotope-labeled compound.
- Endogenous metabolite.
- Inhibitor.
- Targets CaSR and is relevant for cardiovascular disease.
Medchemexpress LLC Aminoadipic acid-d3 | 2483832-01-3 | 99.1% | 164.17 | 10 MG
Aminoadipic acid-d3 is the deuterium labeled Aminoadipic acid, an intermediate in the metabolism of lysine and saccharopine. Deuterium substitution has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Vinorelbine-d3 (ditartrate) | 125317-39-7 | 98.0% | 1082.12 | 100 UG
Vinorelbine-d3 ditartrate is a deuterium labeled version of Vinorelbine ditartrate, an anti-mitotic agent that inhibits the proliferation of Hela cells with an IC50 of 1.25 nM. This compound serves as a valuable tracer and internal standard for quantitative analysis in various analytical techniques.
- Deuterium labeled compound for precise research.
- Inhibits Hela cell proliferation, acting as an anti-mitotic agent.
- Functions as a tracer in drug development processes.
- Ideal as an internal standard for NMR, GC-MS, or LC-MS quantitative analysis.
- Deuteration can influence pharmacokinetic and metabolic profiles of drugs.
Cambridge Isotope Laboratories Hexamethylcyclotrisiloxane D3 (unlabeled) 100 ug/mL in MTBE 1 2 mL
Hexamethylcyclotrisiloxane D3 (unlabeled) 100 ug/mL in MTBE 1 2 mL
Cambridge Isotope Laboratories Ethylmalonic acid (methyl-D3 98%) 0 1 g
Ethylmalonic acid (methyl-D3 98%) 0 1 g
Cambridge Isotope Laboratories 24R 25-Dihydroxyvitamin D3 (25 26 27-13C3 98%) 50 ug/mL in ethanol 1 mL
24R 25-Dihydroxyvitamin D3 (25 26 27-13C3 98%) 50 ug/mL in ethanol 1 mL
Medchemexpress LLC Glycine-2,2-d2, n-(1-oxobutyl)- | 1219799-10-6 | 99.2% | 147.17 g/mol | C6H9D2NO3 | 5 MG
N-Butyrylglycine-d2 is the deuterium-labeled form of N-butyrylglycine intended for laboratory research. It is provided as a high-purity isotopically labeled standard for use in analytical, tracer, and metabolic studies. The material is supplied with supporting analytical documentation and is for research use only.
- Deuterium-labeled (d2) isotopologue.
- High purity: 99.2% (nominal).
- Verified molecular weight: 147.17 g/mol.
- Chemical formula C6H9D2NO3.
- Certificates available: COA, HNMR, RP-HPLC, SDS.
- Available in small mg pack sizes suitable for analytical use.
Cayman Chemical HeptadecnoIc AcId-d3 10mg
An internal standard for the quantification of heptadecanoicacid by GC- or LC-MS
Medchemexpress LLC Alogliptin-d3 | 1133421-35-8 | 99.6% | C18H18D3N5O2 | 1 MG
Alogliptin-d3 is the deuterium labeled Alogliptin, a potent, selective, and orally active inhibitor of DPP-4 with an IC50 of <10 nM. It exhibits over 10,000-fold selectivity for DPP-8 and DPP-9 and can be used for research on type 2 diabetes. Deuterated compounds like Alogliptin-d3 are often used as tracers or internal standards for quantitative analysis.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Valuable for research on type 2 diabetes
- Potent, selective, and orally active inhibitor of DPP-4
- Exhibits over 10,000-fold selectivity for DPP-8 and DPP-9
Medchemexpress LLC D3/5-HT receptor modulator-1 | 898532-85-9 | 99.8% | 391.51 g·mol⁻¹ | C24H29N3O2 | 5 MG
D3/5-HT receptor modulator-1 (compound 5i) is a small-molecule research reagent with a mixed dopaminergic and serotonergic profile. It functions as a selective dopamine D3 receptor antagonist, a 5-HT2A receptor antagonist, and a partial 5-HT1A receptor agonist, and is intended for in vitro and preclinical studies investigating receptor pharmacology and antipsychotic-like mechanisms.
- Selective dopamine D3 receptor antagonist, 5-HT2A receptor antagonist, and partial 5-HT1A receptor agonist.
- High purity (≈99.8%).
- Molecular formula C24H29N3O2 and molecular weight 391.51 g·mol⁻¹.
- Suitable for in vitro and preclinical receptor pharmacology studies.
- Available in small milligram packages for assay screening.
Medchemexpress LLC (R)-(-)-Ibuprofen-d3 | 121702-86-1 | 100.0% | C13H15D3O2 | 1 MG
This deuterium-labeled compound, (R)-(-)-Ibuprofen-d3, serves as the R enantiomer of Ibuprofen. It is inactive on COX and functions as an inhibitor of NF-κB activation, demonstrating anti-inflammatory and antinociceptive effects.
- Can be used as a tracer
- Suitable as an internal standard for quantitative analysis
- Ideal for use in NMR, GC-MS, or LC-MS
Medchemexpress LLC Vitamin D2 (ergocalciferol) | 50-14-6 | 99.1% | C28H44O | 10 G
Vitamin D2 (Ergocalciferol) is derived from plant sources or dietary supplements and can be used as a supplement of Vitamin D. This product is intended for research use only.
- Derived from plant sources
- Can be used as a supplement of vitamin D
- For research use only
- Molecular weight: 396.65
- Appearance: solid
- Color: white to light yellow
- Structure classification: steroids
- Initial source: plants other families
- Endogenous metabolite: human gut microbiota metabolites
- Shipping at room temperature in continental US
- Store at -20°C, protected from light, under nitrogen
- Unstable in solutions; freshly prepared is recommended
- Solubility (in vitro): DMSO: 31.25 mg/mL (78.78 mM)
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eMolecules 1027801-74-6 | MHAPC-Chol | Broadpharm544.865 | C34H60N2O3 | 0.000 | CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@H](CC[C@]4(C)[C@H]3CC[C@]12C)OC(=O)NCCCN(C)CCO | 1mg | 779524211
MHAPC-Chol | Broadpharm | 1027801-74-6544.865 | C34H60N2O3 | 0.000 | CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@H](CC[C@]4(C)[C@H]3CC[C@]12C)OC(=O)NCCCN(C)CCO | 1mg | 779524211
Cayman Chemical 25hydroxy VItamIn D3 3 3am 5mg
A vitamin D3 analog; contains a highly reactive amine group that can be coupled to a sepharose matrix for affinity purification of vitamin D binding protein; inhibits 25-hydroxy vitamin D3-1α-hydroxylase